Testing Potential Inhibitors of the Sigma E Pathway in Escherichia Coli
The bacterial σE-Pathway is a vital stress response pathway that allows bacteria to survive in conditions that would disrupt the cell envelope. Disrupting this pathway with novel chemical inhibitors may lead to the production of innovate antimicrobial therapeutics. Screening with fluorescence-based assays identified several compounds with potential inhibitory activity. From this, the compounds were characterized for their efficacy and inhibitory profiles against Escherichia Coli.
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Work Title Testing Potential Inhibitors of the Sigma E Pathway in Escherichia Coli Access Creators - Kushagra Kumar
Keyword - cell envelope
- Sigma E
- stress response
- signal transduction
- undergraduate research award
- undergraduate research
- University Park
License CC BY 4.0 (Attribution) Work Type Poster Deposited May 02, 2019 Versions
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