Testing Potential Inhibitors of the Sigma E Pathway in Escherichia Coli

The bacterial σE-Pathway is a vital stress response pathway that allows bacteria to survive in conditions that would disrupt the cell envelope. Disrupting this pathway with novel chemical inhibitors may lead to the production of innovate antimicrobial therapeutics. Screening with fluorescence-based assays identified several compounds with potential inhibitory activity. From this, the compounds were characterized for their efficacy and inhibitory profiles against Escherichia Coli.

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Work Title Testing Potential Inhibitors of the Sigma E Pathway in Escherichia Coli
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Open Access
Creators
  1. Kushagra Kumar
Keyword
  1. cell envelope
  2. Sigma E
  3. stress response
  4. signal transduction
  5. undergraduate research award
  6. undergraduate research
  7. University Park
License Attribution 4.0 International (CC BY 4.0)
Work Type Poster
Deposited May 02, 2019

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Version 1
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  • Created
  • Added Kumar_UGR_poster.pdf
  • Added Creator Kushagra Kumar
  • Published