Practical Metabolomics Course Development Resources
Metabolomics is a highly interdisciplinary field and has undergone rapid advancement in the three decades since its inception. Scientists wishing to incorporate metabolomics in their research approaches must apply knowledge from a variety of disciplines, from analytical chemistry to multivariate statistics. However, educational and training opportunities are lacking, and many available resources are short-term in nature and focused on expanding the skillset of those already familiar with metabolomics principles, potentially overlooking those newer to the discipline. To address this gap, a graduate course was developed to provide a practical, hands-on approach to teach metabolomics concepts and methods. Centered around active-learning modules, supplemented with lectures, seminars, and tutorials, students are guided through all aspects of a metabolomics experiment, from experimental design to data collection, processing, analysis, and inference. Students have responded positively to this learner-centered approach and report a deep understanding of the material and confidence in using metabolomics protocols in future experiments.
Files
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View: Manuscript Presentation Rubric.docx
Download: Manuscript Presentation Rubric.docx
View: Metabolomics Annotated Bibliography.docx
Download: Metabolomics Annotated Bibliography.docx
View: Metabolomics Course_README.txt
Download: Metabolomics Course_README.txt
View: Metabolomics Data Project.docx
Download: Metabolomics Data Project.docx
View: Mouse Metabolomics Dataset_metadata.xlsx
Download: Mouse Metabolomics Dataset_metadata.xlsx
View: Mouse Metabolomics Dataset.zip
Download: Mouse Metabolomics Dataset.zip
View: Software Requirements.docx
Download: Software Requirements.docx
View: Workshop1-MS Data Processing-Sample Student Results.csv
Download: Workshop1-MS Data Processing-Sample Student Results.csv
View: Workshop1-MZmine_parameters.csv
Download: Workshop1-MZmine_parameters.csv
View: Workshop2-Statistical Analysis-Sample Student Results.zip
Download: Workshop2-Statistical Analysis-Sample Student Results.zip
View: Workshop3-Data Annotation-Sample Student Results.tar
Download: Workshop3-Data Annotation-Sample Student Results.tar
Metadata
Work Title Practical Metabolomics Course Development Resources Access Creators - Joshua Kellogg
License CC BY-ND 4.0 (Attribution-NoDerivatives) Work Type Project Acknowledgments - We are grateful for to the Huck Institutes’ Metabolomics Core Facility Director Dr. Ashley Shay (RRID:SCR_023864), and the Penn State NMR Facility Director Dr. Tapas Mal for their enthusiastic support of the students and course. This work is supported by the USDA National Institute of Food and Agriculture and Hatch Appropriations under Project #PEN04956 and Accession #7006496.
Publication Date 2025 Subject - Metabolomics
- Mass Spectrometry
- Chemical Education
- Analytical Chemistry
- Course Design
- Chemometrics
- Inquiry-based Learning
Language - English
Deposited May 05, 2025 Versions
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Version 1
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Updated Subject, Language, Description, and 1 more Show ChangesSubjectLanguage
- Metabolomics, Mass Spectrometry, Chemical Education, Analytical Chemistry, Course Design, Chemometrics, Inquiry-based Learning
Description- English
Publication Date- Metabolomics is a highly interdisciplinary field and has undergone rapid advancement in the three decades since its inception. Scientists wishing to incorporate metabolomics in their research approaches must apply knowledge from a variety of disciplines, from analytical chemistry to multivariate statistics. However, educational and training opportunities are lacking, and many available resources are short-term in nature and focused on expanding the skillset of those already familiar with metabolomics principles, potentially overlooking those newer to the discipline. To address this gap, a graduate course was developed to provide a practical, hands-on approach to teach metabolomics concepts and methods. Centered around active-learning modules, supplemented with lectures, seminars, and tutorials, students are guided through all aspects of a metabolomics experiment, from experimental design to data collection, processing, analysis, and inference. Students have responded positively to this learner-centered approach and report a deep understanding of the material and confidence in using metabolomics protocols in future experiments.
- 2025
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Updated Acknowledgments Show ChangesAcknowledgments
- We are grateful for to the Huck Institutes’ Metabolomics Core Facility Director Dr. Ashley Shay (RRID:SCR_023864), and the Penn State NMR Facility Director Dr. Tapas Mal for their enthusiastic support of the students and course. This work is supported by the USDA National Institute of Food and Agriculture and Hatch Appropriations under Project #PEN04956 and Accession #7006496.
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Practical Metabolomics Course Development- Practical Metabolomics Course Development Resources
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- https://creativecommons.org/licenses/by-nd/4.0/
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