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Benralizumab as an Adjuvant Therapy for Recurrent Laryngeal Papillomatosis

Recurrent respiratory (RRP) or laryngeal papillomatosis is the result of human papillomavirus-mediated benign tumor growth on the larynx and is challenging to manage. Benralizumab is a monoclonal antibody targeted against the alpha subunit of the IL-5 receptor on eosinophils. A 61-year-old male patient presented with refractory RRP following multiple surgical excisions. His disease course improved substantially when benralizumab was added to his asthma regimen. There is no clear mechanistic role suggested for benralizumab directly treating RRP. This case may represent a novel application of benralizumab as an adjuvant treatment for patients with RRP and comorbid asthma. Laryngoscope, 2022.

This is the peer reviewed version of the following article: [Benralizumab as an Adjuvant Therapy for Recurrent Laryngeal Papillomatosis. The Laryngoscope 133, 4 p863-865 (2022)], which has been published in final form at https://doi.org/10.1002/lary.30527. This article may be used for non-commercial purposes in accordance with Wiley Terms and Conditions for Use of Self-Archived Versions: https://authorservices.wiley.com/author-resources/Journal-Authors/licensing/self-archiving.html#3.

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Metadata

Work Title Benralizumab as an Adjuvant Therapy for Recurrent Laryngeal Papillomatosis
Access
Open Access
Creators
  1. Kayla J. Krause
  2. David Goldrich
  3. John Gniady
License In Copyright (Rights Reserved)
Work Type Article
Publisher
  1. Laryngoscope
Publication Date December 16, 2022
Publisher Identifier (DOI)
  1. https://doi.org/10.1002/lary.30527
Deposited January 27, 2025

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  • Created

    January 27, 2025 09:25 by Researcher Metadata Database

  • Added Benralizumab-Recurrent-Laryngeal-Papillomatosis.docx

    January 27, 2025 09:25 by Researcher Metadata Database

  • Added Creator Kayla J. Krause

    January 27, 2025 09:25 by Researcher Metadata Database

  • Added Creator David Goldrich

    January 27, 2025 09:25 by Researcher Metadata Database

  • Added Creator John Gniady

    January 27, 2025 09:25 by Researcher Metadata Database

  • Published

    January 27, 2025 09:25 by Researcher Metadata Database

  • Updated

    January 27, 2025 21:04 by [unknown user]

  • Updated Publication Date Show Changes

    March 17, 2026 18:46 by jts5573

    Publication Date
    • 2022-01-01
    • 2022-12-16