Effects of VAD-Induced Shear Rates on Platelet Adhesion
Acquired von Willebrand syndrome is a disease present in many patients with ventricular assist devices (VAD) which causes dysfunction in the protein von Willebrand factor (vWF). This study shows how shear rates seen in VAD-induced flow can affect platelet adhesion due to platelet dependence on vWF interactions. Shear rate and presence of vWF cleaving protease ADAMTS-13 are shown to have a significant effect on the ability of platelets to adhere to an injury site.
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Metadata
| Work Title | Effects of VAD-Induced Shear Rates on Platelet Adhesion |
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| License | CC BY 4.0 (Attribution) |
| Work Type | Poster |
| Publication Date | 2021 |
| Deposited | May 15, 2021 |