Acceptability of electronic nicotine delivery systems (ENDS) among HIV positive smokers

Electronic nicotine delivery systems (ENDS) have the potential to help smokers living with HIV/AIDS (PLWHA) to reduce harms from tobacco use. However, little is known about ENDS use among PLWHA. This study's aim was to evaluate the acceptability of two types of ENDS among PLWHA not planning to quit smoking. The study utilized a cross-over design where participants used two ENDS in a random order as smoking substitutes during two use periods separated by 7 days. Exhaled carbon monoxide (CO) was analyzed and participants reported daily cigarette and ENDS use and completed ratings on ENDS acceptability. Participants (n = 17) were a mean age of 49.1 years (SD = 8.8), were 53% white, and 59% male. All participants had controlled HIV disease status. Participants smoked a mean of 16.9 (SD = 7.9) CPD at baseline. Overall, CPD significantly decreased during both ENDS use periods (p < .01) but there were no differences in reduction between the different devices. CO decreased from baseline to follow-up only during the button-activated ENDS use period (p = .03), but there were no differences between ENDS devices. There were no significant differences in ratings of acceptability between ENDS devices. These results suggest that ENDS could be a harm reduction tool for smokers with HIV.



Work Title Acceptability of electronic nicotine delivery systems (ENDS) among HIV positive smokers
Open Access
  1. Jessica Yingst
  2. Jonathan A Foulds
  3. John Zurlo
  4. Michael Steinberg
  5. Thomas Eissenberg
  6. Ping Du
License CC BY-NC-ND 4.0 (Attribution-NonCommercial-NoDerivatives)
Work Type Article
Publication Date October 2020
Deposited March 29, 2021




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Work History

Version 1

  • Created
  • Added Creator Jessica Yingst
  • Added Creator Jonathan A Foulds
  • Added Creator John Zurlo
  • Added Creator Michael Steinberg
  • Added Creator Thomas Eissenberg
  • Added Creator Ping Du
  • Added Yingst 2019 - Ecig Acceptability HIV patients.pdf
  • Updated License Show Changes
  • Published
  • Updated