The Effects of Choline Supplementation on Blood Pressure Regulation in a Mouse Model of Fetal Alcohol Spectrum Disorder

Prenatal alcohol exposure (PAE) harms a growing fetus, triggering a condition known as fetal alcohol spectrum disorder (FASD). FASD causes learning disabilities and attention deficiencies, however research also suggests physiological symptoms such as hypertension. We analyzed the cardiovascular effects of PAE through blood pressure within mice models. Sex differences for blood pressures between male and female mice in models of FASD were significant, and choline has effects on blood pressure at week 12 and 24.