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Analyzing Diagnostic Studies for Disseminated Intravascular Coagulation: Rotational Thromboelastometry Versus Standard Coagulation Tests

Disseminated intravascular coagulation (DIC) is a life-threatening condition characterized by abnormal clotting and bleeding, often leading to multi-organ failure. Early detection is crucial for improving patient outcomes; however, traditional coagulation tests, such as PT, aPTT, D-dimer, and fibrinogen, may not provide prompt or detailed results. Rotational Thromboelastometry (ROTEM) provides a rapid assessment of coagulation metrics, thereby enhancing diagnostic accuracy and treatment efficiency. However, its high cost raises concerns regarding its feasibility in hospital settings. This project aims to address these concerns by examining how ROTEM compares to standard coagulation tests (PT, aPTT, D-dimer, fibrinogen) regarding diagnostic accuracy, efficiency, and cost in trauma patients at risk of developing DIC.

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Work Title Analyzing Diagnostic Studies for Disseminated Intravascular Coagulation: Rotational Thromboelastometry Versus Standard Coagulation Tests
Access
Open Access
Creators
  1. Yara Amleh
Keyword
  1. Penn State Mont Alto Academic Festival 2025
  2. Undergraduate Research
  3. ROTEM
  4. DIC
License CC BY 4.0 (Attribution)
Work Type Poster
Acknowledgments
  1. Faculty Mentor: Joan Krug
Publication Date April 25, 2025
Related URLs
  1. https://montalto.psu.edu/academics/festival
Deposited April 17, 2025

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Version 1
published

  • Created

    April 17, 2025 14:47 by tlr15

  • Updated

    April 17, 2025 14:47 by [unknown user]

  • Updated Keyword, Related URLs, Description, and 1 more Show Changes

    April 17, 2025 14:48 by tlr15

    Keyword
    • Penn State Mont Alto Academic Festival 2025, Undergraduate Research
    Related URLs
    • https://montalto.psu.edu/academics/festival
    Description
    • Disseminated intravascular coagulation (DIC) is a life-threatening condition characterized by abnormal clotting and bleeding, often leading to multi-organ failure. Early detection is crucial for improving patient outcomes; however, traditional coagulation tests, such as PT, aPTT, D-dimer, and fibrinogen, may not provide prompt or detailed results. Rotational Thromboelastometry (ROTEM) provides a rapid assessment of coagulation metrics, thereby enhancing diagnostic accuracy and treatment efficiency. However, its high cost raises concerns regarding its feasibility in hospital settings. This project aims to address these concerns by examining how ROTEM compares to standard coagulation tests (PT, aPTT, D-dimer, fibrinogen) regarding diagnostic accuracy, efficiency, and cost in trauma patients at risk of developing DIC.
    Publication Date
    • 2025-04-25
  • Updated Acknowledgments Show Changes

    April 17, 2025 14:48 by tlr15

    Acknowledgments
    • Faculty Mentor: Joan Krug
  • Added Creator Yara Amleh

    April 17, 2025 14:48 by tlr15

  • Added 60 Analyzing Diagnostic Studies.pdf

    April 17, 2025 14:49 by tlr15

  • Updated License Show Changes

    April 17, 2025 14:49 by tlr15

    License
    • https://creativecommons.org/licenses/by/4.0/
  • Published

    April 17, 2025 14:49 by tlr15

  • Updated

    April 17, 2025 22:05 by [unknown user]

  • Updated Keyword Show Changes

    May 20, 2025 12:37 by jts5573

    Keyword
    • Penn State Mont Alto Academic Festival 2025, Undergraduate Research
    • Penn State Mont Alto Academic Festival 2025, Undergraduate Research, ROTEM , DIC