Data Sharing Files for "Deletion of the stress response protein REDD1 prevents sodium iodate-induced RPE damage and photoreceptor loss"

The studies here explored a role for the stress response protein Regulated in Development and DNA damage response 1 (REDD1) in the development of retinal pathology by using the oxidant stressor sodium iodate (NaIO3) to model dry AMD in mice. Overall, REDD1 deletion was sufficient to prevent retinal oxidative stress, RPE damage, immune cell activation, and photoreceptor loss in response to NaIO3.

Citation

Dennis, Michael (2024). Data Sharing Files for "Deletion of the stress response protein REDD1 prevents sodium iodate-induced RPE damage and photoreceptor loss" [Data set]. Scholarsphere. https://doi.org/10.26207/e2fb-pg21

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Work Title Data Sharing Files for "Deletion of the stress response protein REDD1 prevents sodium iodate-induced RPE damage and photoreceptor loss"
Access
Open Access
Creators
  1. Michael Don Dennis
Keyword
  1. DDIT4
  2. RTP801
  3. Retinal pigmented epithelium
  4. Aging
License CC BY-NC 4.0 (Attribution-NonCommercial)
Work Type Dataset
Publication Date November 2024
DOI doi:10.26207/e2fb-pg21
Related URLs
Deposited October 09, 2024

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Version 1
published

  • Created
  • Updated
  • Added Creator Michael Don Dennis
  • Added All figures data.xlsx
  • Added README.docx
  • Deleted README.docx
  • Added README.docx
  • Updated License, Description, Publication Date Show Changes
    License
    • https://creativecommons.org/licenses/by-nc/4.0/
    Description
    • The studies here explored a role for the stress response protein Regulated in Development and DNA damage response 1 (REDD1) in the development of retinal pathology by using the oxidant stressor sodium iodate (NaIO3) to model dry AMD in mice. Overall, REDD1 deletion was sufficient to prevent retinal oxidative stress, RPE damage, immune cell activation, and photoreceptor loss in response to NaIO3.
    Publication Date
    • 2024-11
  • Published
  • Updated
  • Updated Work Title Show Changes
    Work Title
    • Data Sharing Files for "Deletion of the stress response protein REDD1 prevents sodium iodate-induced RPE damaage and photoreceptor loss"
    • Data Sharing Files for "Deletion of the stress response protein REDD1 prevents sodium iodate-induced RPE damage and photoreceptor loss"
  • Updated Keyword, Related URLs Show Changes
    Keyword
    • DDIT4, RTP801, Retinal pigmented epithelium, Aging
    Related URLs
    • https://doi.org/10.1007/s11357-024-01362-2