Wild goldenseal (Hydrastis canadensis L.) rhizome/root alkaloid content in relation to colony and harvest stage

This study examined the three major alkaloids (berberine, hydrastine, and canadine) in wild goldenseal (Hydrastis canadensis) roots and rhizomes in relation to plant colony and harvest stage. Goldenseal colonies in central Pennsylvania, USA, were sampled on four dates (July 2, August 7, September 8, and October 12) corresponding with observable phenological stages between fruit maturity and senescence. Variation was observed for all three alkaloids with berberine and hydrastine present in all colonies and samples, while canadine was not detected during some late season sample dates. Nineteen root samples (53%) met the established United States Pharmacopeia (USP) standards for berberine content, while only one sample (2.8%) met USP standards for hydrastine. All colonies and samples showed an increase in alkaloid levels at the time of senescence, which corroborated the industry guidance that rhizomes/roots should be harvested at senescence (typically during the Fall season). Harvesting at senescence also permits fruit to mature and thereby facilitates sexual reproduction. However, alkaloid levels averaged the second highest at fruit maturity (July 2) which suggested that alkaloids may fluctuate during the growing season in response to, or as a function of, key reproductive events.

This is an Accepted Manuscript of an article published by Taylor & Francis in Journal of Herbs, Spices & Medicinal Plants on 2019-04-03, available online: https://www.tandfonline.com/10.1080/10496475.2019.1577322.

Files

Metadata

Work Title Wild goldenseal (Hydrastis canadensis L.) rhizome/root alkaloid content in relation to colony and harvest stage
Access
Open Access
Creators
  1. Eric P. Burkhart
  2. Grady H. Zuiderveen
Keyword
  1. Alkaloids
  2. berberine
  3. medicinal plant chemistry
  4. phytochemistry
  5. secondary metabolites
License CC BY-NC 4.0 (Attribution-NonCommercial)
Work Type Article
Publisher
  1. Journal of Herbs, Spices and Medicinal Plants
Publication Date February 22, 2019
Publisher Identifier (DOI)
  1. https://doi.org/10.1080/10496475.2019.1577322
Deposited July 19, 2024

Versions

Analytics

Collections

This resource is currently not in any collection.

Work History

Version 1
published

  • Created
  • Added _system_appendPDF_proof_hi.pdf
  • Added Creator Eric P. Burkhart
  • Added Creator Grady H. Zuiderveen
  • Published
  • Updated
  • Updated Keyword Show Changes
    Keyword
    • Alkaloids, berberine, medicinal plant chemistry, phytochemistry, secondary metabolites
  • Updated Work Title Show Changes
    Work Title
    • Wild goldenseal (Hydrastis canadensis) rhizome/root alkaloid content in relation to colony and harvest stage
    • Wild goldenseal (Hydrastis canadensis L.) rhizome/root alkaloid content in relation to colony and harvest stage
  • Deleted _system_appendPDF_proof_hi.pdf
  • Added Goldenseal_Chemistry_Manuscript_Title_Page_Final_2018_v2.docx
  • Added Goldenseal_Chemistry_Manuscript_Figures_Final_2018_v2.docx
  • Added Goldenseal_Chemistry_Manuscript_Tables_Final_2018_v2.docx
  • Added Goldenseal_Chemistry_Manuscript_Revised_Final_2018_v3.docx