CRISPR Technology and Congenital Disordered Development

People from all over the globe suffer from congenital disorders that inevitably cause lifelong challenges. The purpose of the research is to evaluate CRISPR’s ability to reduce the occurrence of genetic abnormalities in in vitro fertilization. The search for literature was conducted on PubMed and Web of Science. Key phrases that were searched were CRISPR/Cas9, CRISPR-Cas9, in vitro fertilization, IVF, and congenital disorders. Eight research articles that were selected assessed CRISPR's use in editing selected genomes. Two other articles described how CRISPR was implemented within their individual studies. Overall, the common theme within the articles is that genome editing in in vitro models is possible with CRISPR technology. Therefore, there is the possibility that as technology advances, we might see fewer congenital disorder diagnoses because of genetic modification.


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Work Title CRISPR Technology and Congenital Disordered Development
Open Access
  1. Maegan Aleshire
  2. Abigail Keiser
  3. Taylor Nicole Peachey
  1. Penn State Mont Alto Academic Festival 2022
  2. Undergraduate Research
License CC BY 4.0 (Attribution)
Work Type Poster
Publication Date April 22, 2022
Related URLs
Deposited April 18, 2022




Work History

Version 1

  • Created
  • Updated
  • Added Creator Maegan Aleshire
  • Added Creator Abigail Keiser
  • Added Creator Taylor Nicole Peachey
  • Added CRISPR Technology.pdf
  • Updated License Show Changes
  • Published