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Created
February 07, 2024 12:04
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Researcher Metadata Database
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2022-ATS-Perfusion_Modalities-Undar.pdf
February 07, 2024 12:04
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2021-Circuit_Optimization_-_GME_counts-WJPCHS.pdf
February 07, 2024 12:04
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Researcher Metadata Database
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2022-Highlights_of_the_Sixteenth_International_Conference_on_Pediatric_Mechanical_Circulatory_Support_Systems_and_Pediatric_Cardiopulmonary_Perfusion.pdf
February 07, 2024 12:04
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Researcher Metadata Database
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2022-WJPCHS-Centrifugal_Pump_Generates_Superior_Hemodynamic_Performance_Compared_to_a_new_Diagonal_Blood_Pump_in_Neonatal_and_Pediatric_ECMO_Circuits-Patel.pdf
February 07, 2024 12:04
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Researcher Metadata Database
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2022-WJPCHS-Impact_of_a_Multidisciplinary_Research_Team_Approach_to_Prevent_Avoidable_Mistakes_for_Neonatal_CPB_Population-Patel.pdf
February 07, 2024 12:04
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2023_-_JTCVS_Open_-_AATS_-_Pulsatile_Flow-Penn_State.pdf
February 07, 2024 12:04
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2023-Perfusion-MUF.pdf
February 07, 2024 12:04
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2023-Undar_et_al_-_PCCM-centrifugal_or_roller_blood_pumps_for_neonatal.5__2___1_.pdf
February 07, 2024 12:04
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Researcher Metadata Database
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undar-2020-pressure-and-flow-properties-of-dual-lumen-cannulae-for-extracorporeal-membrane-oxygenation__1_.pdf
February 07, 2024 12:04
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Researcher Metadata Database
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Added Creator Akif Ündar
February 07, 2024 12:04
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Added Creator Allen R. Kunselman
February 07, 2024 12:04
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Added Creator Ryan P. Barbaro
February 07, 2024 12:04
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Added Creator Peta Alexander
February 07, 2024 12:04
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Researcher Metadata Database
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Added Creator Krishna Patel
February 07, 2024 12:04
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Added Creator Neal J. Thomas
February 07, 2024 12:04
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Published
February 07, 2024 12:04
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Researcher Metadata Database
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Updated
April 04, 2024 10:22
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[unknown user]
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2021-Circuit_Optimization_-_GME_counts-WJPCHS.pdf
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avs5190
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2022-ATS-Perfusion_Modalities-Undar.pdf
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2022-Highlights_of_the_Sixteenth_International_Conference_on_Pediatric_Mechanical_Circulatory_Support_Systems_and_Pediatric_Cardiopulmonary_Perfusion.pdf
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avs5190
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2022-WJPCHS-Centrifugal_Pump_Generates_Superior_Hemodynamic_Performance_Compared_to_a_new_Diagonal_Blood_Pump_in_Neonatal_and_Pediatric_ECMO_Circuits-Patel.pdf
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avs5190
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2022-WJPCHS-Impact_of_a_Multidisciplinary_Research_Team_Approach_to_Prevent_Avoidable_Mistakes_for_Neonatal_CPB_Population-Patel.pdf
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2023_-_JTCVS_Open_-_AATS_-_Pulsatile_Flow-Penn_State.pdf
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2023-Perfusion-MUF.pdf
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undar-2020-pressure-and-flow-properties-of-dual-lumen-cannulae-for-extracorporeal-membrane-oxygenation__1_.pdf
May 24, 2024 11:25
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avs5190
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May 24, 2024 11:29
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avs5190
Keyword
- Centrifugal pumps, Dual-lumen venovenous cannulas, Extracorporeal Life Support Organization registry, Morbidity and mortality, Roller pumps, Venovenous extracorporeal membrane oxygenation
Description
<p>OBJECTIVES: To investigate outcomes associated with conventional roller or centrifugal pumps during neonatal venovenous extracorporeal membrane oxygenation (ECMO). Our primary hypothesis is that in comparison with conventional roller-pump support, centrifugal pump use is associated with greater odds of survival. Our secondary hypothesis is that centrifugal pump use is associated with lesser odds of complications. DESIGN: Retrospective cohort identified using the Extracorporeal Life Support Organization (ELSO) registry 2016 to 2020 dataset. SETTING: All ECMO centers reporting to the ELSO registry. PATIENTS: All neonates (≤ 28 d) supported with venovenous ECMO and cannulated via right internal jugular vein using dual-lumen venovenous cannulas and polymethyl pentene membrane oxygenators. INTERVENTIONS: None. MEASUREMENTS AND MAIN RESULTS: A total of 612 neonates (centrifugal, n = 340; conventional roller, n = 272) were included in the analysis. Using a multivariable logistic regression model, centrifugal pump use - as opposed to roller pump use - was associated with lesser odds of survival (odds ratio [OR], 0.53; 95% CI, 0.33-0.84; p < 0.008). Thrombosis and clots in the circuit components were also associated with lesser odds of survival (OR, 0.28; 95% CI, 0.16-0.60; p < 0.001). We failed to show that hemolysis was an independent variable for survival (OR, 0.60; 95% CI, 0.31-1.19; p = 0.14). The primary diagnosis of neonatal aspiration/meconium aspiration is associated with more than seven-fold greater odds of survival (OR, 7.57; 95% CI, 4.02-15.74; p < 0.001). CONCLUSIONS: Contrary to our hypotheses, conventional roller pump use was associated with greater odds of survival. While thrombosis and clots in circuit components were independent variables for lesser odds of survival, further research is needed better to understand the use of centrifugal pumps in neonatal practice.</p>
- <p>OBJECTIVES: To investigate outcomes associated with conventional roller or centrifugal pumps during neonatal venovenous extracorporeal membrane oxygenation (ECMO). Our primary hypothesis is that in comparison with conventional roller-pump support, centrifugal pump use is associated with greater odds of survival. Our secondary hypothesis is that centrifugal pump use is associated with lesser odds of complications.
- DESIGN: Retrospective cohort identified using the Extracorporeal Life Support Organization (ELSO) registry 2016 to 2020 dataset.
- SETTING: All ECMO centers reporting to the ELSO registry.
- PATIENTS: All neonates (≤ 28 d) supported with venovenous ECMO and cannulated via right internal jugular vein using dual-lumen venovenous cannulas and polymethyl pentene membrane oxygenators.
- INTERVENTIONS: None.
- MEASUREMENTS AND MAIN RESULTS: A total of 612 neonates (centrifugal, n = 340; conventional roller, n = 272) were included in the analysis. Using a multivariable logistic regression model, centrifugal pump use - as opposed to roller pump use - was associated with lesser odds of survival (odds ratio [OR], 0.53; 95% CI, 0.33-0.84; p < 0.008). Thrombosis and clots in the circuit components were also associated with lesser odds of survival (OR, 0.28; 95% CI, 0.16-0.60; p < 0.001). We failed to show that hemolysis was an independent variable for survival (OR, 0.60; 95% CI, 0.31-1.19; p = 0.14). The primary diagnosis of neonatal aspiration/meconium aspiration is associated with more than seven-fold greater odds of survival (OR, 7.57; 95% CI, 4.02-15.74; p < 0.001).
- CONCLUSIONS: Contrary to our hypotheses, conventional roller pump use was associated with greater odds of survival. While thrombosis and clots in circuit components were independent variables for lesser odds of survival, further research is needed better to understand the use of centrifugal pumps in neonatal practice.</p>
Publication Date