Investigating the Molecular Evolution of contig 40 in the Muller D Element of D. bipectinata
The Muller F element is the smallest chromosome in Drosophila species but is significantly larger in D. Bipectinata than most other Drosophila species. Genomics Education Partnership (GEP) launched the F Element Project in order to further understand the expansion of the F Element in D. Bipectinata and its impact on gene characteristics. In partnership with GEP, this study evaluated and annotated contig 40 of the Muller F Element of Drosophila Bipectinata in order to assess the presence of any orthologs that will aid in understanding genome expansion in Drosophila species. This study was performed by using UCSC’s Genome Browser to annotate the coding region and transcription start sites based on various tracks of evidence, including BLASTX alignment to D. Melanogaster proteins and RNA sequencing tracks. The results of this study provided complete annotations for the five D. Bipectinata genes present in contig 40, Ddx1, JMJD7, Rich, Cmb, and CG11523, and their respective isoforms. The comparison of these five genes in D. Bipectinata to those in D. Melanogaster can provide insight into understanding the expansion of the Muller F element when this analysis is combined with data from genes from other Drosophila species with expanded Muller F Elements.
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|Investigating the Molecular Evolution of contig 40 in the Muller D Element of D. bipectinata
|In Copyright (Rights Reserved)
|May 23, 2023