Direct Laser Writing of the Porous Graphene Foam for Multiplexed Electrochemical Sweat Sensors

Wearable electrochemical sensors provide means to detect molecular-level information from the biochemical markers in biofluids for physiological health evaluation. However, a high-density array is often required for multiplexed detection of multiple markers in complex biofluids, which is challenging with low-cost fabrication methods. This work reports the low-cost direct laser writing of porous graphene foam as a flexible electrochemical sensor to detect biomarkers and electrolytes in sweat. The resulting electrochemical sensor exhibits high sensitivity and low limit of detection for various biomarkers (e.g., the sensitivity of 6.49/6.87/0.94/0.16 μA μM^-1cm^-2 and detection limit of 0.28/0.26/1.43/11.3 μM to uric acid/dopamine/tyrosine/ascorbic acid) in sweat. The results from this work open up opportunities for noninvasive continuous monitoring of gout, hydration status, and drug intake/overdose.

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Work Title Direct Laser Writing of the Porous Graphene Foam for Multiplexed Electrochemical Sweat Sensors
Access
Open Access
Creators
  1. Li Yang
  2. He Wang
  3. Abu Musa Abdullah
  4. Chuizhou Meng
  5. Xue Chen
  6. Anqi Feng
  7. Huanyu Cheng
Keyword
  1. Direct laser writing
  2. Porous graphene foam
  3. Wearable electrochemical sweat sensors
  4. Multiplexed biomarker detections
  5. Health monitoring
License In Copyright (Rights Reserved)
Work Type Article
Publisher
  1. ACS Applied Materials & Interfaces
Publication Date July 11, 2023
Publisher Identifier (DOI)
  1. https://doi.org/10.1021/acsami.3c02485
Deposited January 29, 2024

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Version 1
published

  • Created
  • Added Revised_manuscript.docx
  • Added Creator Li Yang
  • Added Creator He Wang
  • Added Creator Abu Musa Abdullah
  • Added Creator Chuizhou Meng
  • Added Creator Xue Chen
  • Added Creator Anqi Feng
  • Added Creator Huanyu Cheng
  • Published
  • Updated Keyword, Publisher, Description, and 1 more Show Changes
    Keyword
    • Direct laser writing, Porous graphene foam, Wearable electrochemical sweat sensors, Multiplexed biomarker detections, Health monitoring
    Publisher
    • ACS applied materials & interfaces
    • ACS Applied Materials & Interfaces
    Description
    • <p>Wearable electrochemical sensors provide means to detect molecular-level information from the biochemical markers in biofluids for physiological health evaluation. However, a high-density array is often required for multiplexed detection of multiple markers in complex biofluids, which is challenging with low-cost fabrication methods. This work reports the low-cost direct laser writing of porous graphene foam as a flexible electrochemical sensor to detect biomarkers and electrolytes in sweat. The resulting electrochemical sensor exhibits high sensitivity and low limit of detection for various biomarkers (e.g., the sensitivity of 6.49/6.87/0.94/0.16 μA μM<sup>-1</sup> cm<sup>-2</sup> and detection limit of 0.28/0.26/1.43/11.3 μM to uric acid/dopamine/tyrosine/ascorbic acid) in sweat. The results from this work open up opportunities for noninvasive continuous monitoring of gout, hydration status, and drug intake/overdose.</p>
    • <p>Wearable electrochemical sensors provide means to detect molecular-level information from the biochemical markers in biofluids for physiological health evaluation. However, a high-density array is often required for multiplexed detection of multiple markers in complex biofluids, which is challenging with low-cost fabrication methods. This work reports the low-cost direct laser writing of porous graphene foam as a flexible electrochemical sensor to detect biomarkers and electrolytes in sweat. The resulting electrochemical sensor exhibits high sensitivity and low limit of detection for various biomarkers (e.g., the sensitivity of 6.49/6.87/0.94/0.16 μA μM^-1cm^-2 and detection limit of 0.28/0.26/1.43/11.3 μM to uric acid/dopamine/tyrosine/ascorbic acid) in sweat. The results from this work open up opportunities for noninvasive continuous monitoring of gout, hydration status, and drug intake/overdose.</p>
    Publication Date
    • 2023-07-26
    • 2023-07-11
  • Updated