ScholarSphere

High Cannabigerol Hemp Extract Moderates Colitis and Modulates the Microbiome in an Inflammatory Bowel Disease Model

Raw mass spectral dataset from mice treated with hemp extract and induced with irritable bowel disease (via DSS administration). 6–8-week-old, male C57BL/6J mice were treated with 2% DSS to induce colitis. Animals were treated with vehicle, or a high-CBG hemp extract by intraperitoneal injection. Fresh stool samples were collected at day 0, 5, and 7.

Published as: Anderson, Benjamin D., Diana E. Sepulveda, Rahul Nachnani, Alonso Cortez-Resendiz, Matthew D. Coates, Aviauna Beckett, Jordan E. Bisanz, Joshua J. Kellogg, and Wesley M. Raup-Konsavage. “High Cannabigerol Hemp Extract Moderates Colitis and Modulates the Microbiome in an Inflammatory Bowel Disease Model.” Journal of Pharmacology and Experimental Therapeutics 390, no. 3 (September 1, 2024): 331–41. https://doi.org/10.1124/jpet.124.002204.

Citation

Kellogg, Joshua; Raup-Konsavage, Wesley; Bisanz, Jordan; Anderson, Benjamin; Sepulveda, Diana; Nachani, Rahul; Cortez-Resendi, Alonso; Coates, Matthew; Beckett, Aviauna (2024). High Cannabigerol Hemp Extract Moderates Colitis and Modulates the Microbiome in an Inflammatory Bowel Disease Model [Data set]. Scholarsphere. https://doi.org/10.26207/jfjm-9490

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Metadata

Work Title High Cannabigerol Hemp Extract Moderates Colitis and Modulates the Microbiome in an Inflammatory Bowel Disease Model
Access
Open Access
Creators
  1. Joshua Kellogg
  2. Wesley Raup-Konsavage
  3. Jordan Bisanz
  4. Benjamin Davis Anderson
  5. Diana Sepulveda
  6. Rahul Nachani
  7. Alonso Cortez-Resendi
  8. Matthew Coates
  9. Aviauna Beckett
Keyword
  1. cannabis
  2. Inflammatory Bowel Disease
  3. hemp
  4. in vivo
  5. cannabigerol
  6. cannabidiol
License CC BY-NC 4.0 (Attribution-NonCommercial)
Work Type Dataset
Acknowledgments
  1. Huck Institutes’ Metabolomics Core Facility (RRID:SCR_023864)
Publication Date 2024
Language
  1. English
DOI doi:10.26207/jfjm-9490
Related URLs
  1. https://doi.org/10.1124/jpet.124.002204
Deposited February 07, 2025

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Work History

Version 1
published

  • Created

    February 07, 2025 13:50 by jjk6146

  • Updated

    February 07, 2025 13:50 by [unknown user]

  • Updated Work Title Show Changes

    February 27, 2025 17:17 by jjk6146

    Work Title
    • Test
    • Mouse Metabolomics Dataset
  • Updated Keyword, Description, Publication Date Show Changes

    February 27, 2025 17:23 by jjk6146

    Keyword
    • cannabis
    Description
    • Raw mass spectral dataset from mice treated with hemp extract and induced with irritable bowel disease (via DSS administration).
    • Published as Anderson, Benjamin D., Diana E. Sepulveda, Rahul Nachnani, Alonso Cortez-Resendiz, Matthew D. Coates, Aviauna Beckett, Jordan E. Bisanz, Joshua J. Kellogg, and Wesley M. Raup-Konsavage. “High Cannabigerol Hemp Extract Moderates Colitis and Modulates the Microbiome in an Inflammatory Bowel Disease Model.” Journal of Pharmacology and Experimental Therapeutics 390, no. 3 (September 1, 2024): 331–41. https://doi.org/10.1124/jpet.124.002204.
    Publication Date
    • 2024
  • Updated Keyword, Language, Related URLs Show Changes

    February 27, 2025 17:26 by jjk6146

    Keyword
    • cannabis
    • cannabis, Inflammatory Bowel Disease, hemp, in vivo, cannabigerol, cannabidiol
    Language
    • English
    Related URLs
    • https://jpet.aspetjournals.org/content/390/3/331
  • Added README.txt

    February 27, 2025 23:21 by jjk6146

  • Added Mouse_metadata.csv

    February 27, 2025 23:21 by jjk6146

  • Added Negative Mode MS.zip

    February 27, 2025 23:21 by jjk6146

  • Added Positive Mode MS.zip

    February 27, 2025 23:21 by jjk6146

  • Updated License Show Changes

    February 28, 2025 09:34 by jjk6146

    License
    • https://creativecommons.org/licenses/by-nc/4.0/
  • Updated Work Title Show Changes

    February 28, 2025 09:35 by jjk6146

    Work Title
    • Mouse Metabolomics Dataset
    • Hemp-IBD Mouse Metabolomics Dataset
  • Updated Publisher, Description Show Changes

    February 28, 2025 09:35 by jjk6146

    Publisher
    • Journal of Pharmacology and Experimental Therapeutics
    Description
    • Raw mass spectral dataset from mice treated with hemp extract and induced with irritable bowel disease (via DSS administration).
    • Published as Anderson, Benjamin D., Diana E. Sepulveda, Rahul Nachnani, Alonso Cortez-Resendiz, Matthew D. Coates, Aviauna Beckett, Jordan E. Bisanz, Joshua J. Kellogg, and Wesley M. Raup-Konsavage. “High Cannabigerol Hemp Extract Moderates Colitis and Modulates the Microbiome in an Inflammatory Bowel Disease Model.” Journal of Pharmacology and Experimental Therapeutics 390, no. 3 (September 1, 2024): 331–41. https://doi.org/10.1124/jpet.124.002204.
    • Published as:
    • Anderson, Benjamin D., Diana E. Sepulveda, Rahul Nachnani, Alonso Cortez-Resendiz, Matthew D. Coates, Aviauna Beckett, Jordan E. Bisanz, Joshua J. Kellogg, and Wesley M. Raup-Konsavage. “High Cannabigerol Hemp Extract Moderates Colitis and Modulates the Microbiome in an Inflammatory Bowel Disease Model.” Journal of Pharmacology and Experimental Therapeutics 390, no. 3 (September 1, 2024): 331–41. https://doi.org/10.1124/jpet.124.002204.
  • Updated Acknowledgments Show Changes

    February 28, 2025 09:40 by jjk6146

    Acknowledgments
    • Huck Institutes’ Metabolomics Core Facility (RRID:SCR_023864)
  • Added Creator Joshua Kellogg

    February 28, 2025 09:40 by jjk6146

  • Added Creator Wesley Raup-Konsavage

    February 28, 2025 09:40 by jjk6146

  • Added Creator Jordan Bisanz

    February 28, 2025 09:40 by jjk6146

  • Added Creator Benjamin Davis Anderson

    February 28, 2025 09:40 by jjk6146

  • Added Creator Diana Sepulveda

    February 28, 2025 09:40 by jjk6146

  • Added Creator Rahul Nachani

    February 28, 2025 09:40 by jjk6146

  • Added Creator Alonso Cortez-Resendi

    February 28, 2025 09:40 by jjk6146

  • Added Creator Matthew Coates

    February 28, 2025 09:40 by jjk6146

  • Added Creator Aviauna Beckett

    February 28, 2025 09:40 by jjk6146

  • Updated Work Title Show Changes

    February 28, 2025 09:41 by jjk6146

    Work Title
    • Hemp-IBD Mouse Metabolomics Dataset
    • Stool metabolome from a murine inflammatory bowel disease model treated with hemp extract
  • Updated Description Show Changes

    February 28, 2025 09:41 by jjk6146

    Description
    • Raw mass spectral dataset from mice treated with hemp extract and induced with irritable bowel disease (via DSS administration).
    • Raw mass spectral dataset from mice treated with hemp extract and induced with irritable bowel disease (via DSS administration). 6–8-week-old, male C57BL/6J mice were treated with 2% DSS to induce colitis. Animals were treated with vehicle, or a high-CBG hemp extract by intraperitoneal injection. Fresh stool samples were collected at day 0, 5, and 7.
    • Published as:
    • Anderson, Benjamin D., Diana E. Sepulveda, Rahul Nachnani, Alonso Cortez-Resendiz, Matthew D. Coates, Aviauna Beckett, Jordan E. Bisanz, Joshua J. Kellogg, and Wesley M. Raup-Konsavage. “High Cannabigerol Hemp Extract Moderates Colitis and Modulates the Microbiome in an Inflammatory Bowel Disease Model.” Journal of Pharmacology and Experimental Therapeutics 390, no. 3 (September 1, 2024): 331–41. https://doi.org/10.1124/jpet.124.002204.
  • Published

    February 28, 2025 09:42 by jjk6146

  • Updated

    February 28, 2025 21:04 by [unknown user]

  • Updated Publisher, Related URLs Show Changes

    April 02, 2025 12:53 by avs5190

    Publisher
    • Journal of Pharmacology and Experimental Therapeutics
    Related URLs
    • https://jpet.aspetjournals.org/content/390/3/331
    • https://doi.org/10.1124/jpet.124.002204

Version 2
published

  • Created

    April 03, 2025 11:27 by jjk6146

  • Updated Work Title Show Changes

    April 03, 2025 11:28 by jjk6146

    Work Title
    • Stool metabolome from a murine inflammatory bowel disease model treated with hemp extract
    • High Cannabigerol Hemp Extract Moderates Colitis and Modulates the Microbiome in an Inflammatory Bowel Disease Model
  • Deleted README.txt

    April 03, 2025 11:32 by jjk6146

  • Added README.txt

    April 03, 2025 11:32 by jjk6146

  • Published

    April 03, 2025 11:33 by jjk6146

  • Updated

    April 03, 2025 22:05 by [unknown user]