Longitudinal Links between Adolescent and Peer Conduct Problems and Moderation by a Sensitivity Genetic Index

The most extensively studied influence on adolescent conduct problem behaviors is peers, and the literature points to genetics as one source of individual differences in peer influence. The purpose of this study was to test the hypothesis that an environmental sensitivity genetic index comprised of DRD4, 5-HTTLPR, and GABRA2 variation would moderate the association between peer and adolescent conduct problems. Latent growth modeling was applied to PROSPER project longitudinal data from adolescents and their peers. Results showed the hypothesis was supported; adolescents with more copies of putative sensitivity alleles were more strongly influenced by their peers. The interaction form was consistent with differential susceptibility in follow-up analyses. Strengths and weaknesses of genetic aggregates for sensitivity research are discussed.

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Work Title Longitudinal Links between Adolescent and Peer Conduct Problems and Moderation by a Sensitivity Genetic Index
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Open Access
Creators
  1. Gabriel L Schlomer
  2. H H Cleveland
  3. M E Feinberg
  4. Jessica L Murray
  5. David J Vandenbergh
License In Copyright (Rights Reserved)
Work Type Article
Publisher
  1. Journal of Research on Adolescence
Publication Date October 31, 2020
Publisher Identifier (DOI)
  1. https://doi.org/10.1111/jora.12592
Deposited July 22, 2021

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Version 1
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  • Created
  • Added Schlomer_2021_GeneticSensitivity_PeerConductProblems.docx
  • Added Creator Gabriel L Schlomer
  • Added Creator H H Cleveland
  • Added Creator M E Feinberg
  • Added Creator Jessica L Murray
  • Added Creator David J Vandenbergh
  • Published
  • Updated
  • Updated