Chronic Diseases Associated with Mortality in Adults with COVID-19 in the United States
Pre-existing chronic conditions in COVID-19 patients are risk factors for increasing odds of severe disease and death. In this paper, I aimed to determine the demographic and clinical factors, especially baseline chronic diseases, associated with the mortality in COVID-19 patients who are from 18 to 90 years old. A retrospective cohort study of adults with COVID-19 coded in electronic medical records included 99479 individuals (mean age 59.6 years, 57.99% women) between 20 January and 26 May 2020. I performed machine learning and deep learning to analyze the association between each chronic disease and all-cause mortality for a prediction model. Male sex, older age, being White, congestive heart failure and obstructive sleep apnea increased the risk of severity SARSCoV-2 infections in human. Identifying patient characteristics and comorbid conditions associated with COVID-19 patients in terms of severity and mortality is important for hypothesis developing a comprehensive intervention strategy to manage high-risk patients.
Academic advisor: Dr. Paul Griffin
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|Work Title||Chronic Diseases Associated with Mortality in Adults with COVID-19 in the United States|
|License||In Copyright (Rights Reserved)|
|Work Type||Research Paper|
|Deposited||November 03, 2022|
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