Strain-Tunable Microfluidic Devices with Crack and Wrinkle Microvalves for Microsphere Screening and Fluidic Logic Gates

Mechanical instabilities in soft materials have led to the formation of unique surface patterns such as wrinkles and cracks for a wide range of applications that are related to surface morphologies and their dynamic tuning. Here, we report a simple yet effective strategy to fabricate strain-tunable crack and wrinkle microvalves with dimensions responding to the applied tensile strain. The crack microvalves initially closed before stretching are opened as the tensile strain is applied, whereas the wrinkle microvalves exhibit the opposite trend. Next, the performance of crack and wrinkle microvalves is characterized. The design predictions on the bursting pressure of microvalves and others from the theory agree reasonably well with the experimental measurements. The microfluidic devices with strain-tunable crack and wrinkle microvalves have then been demonstrated for microsphere screening and programmable microfluidic logic devices. The demonstrated microfluidic devices complement the prior studies to open up opportunities in microparticle/cell manipulations, fluidic operations, and biomedicine.

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Work Title Strain-Tunable Microfluidic Devices with Crack and Wrinkle Microvalves for Microsphere Screening and Fluidic Logic Gates
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Open Access
Creators
  1. Ying Liu
  2. Min Cheng
  3. Jielong Huang
  4. Yangchengyi Liu
  5. Yao Chen
  6. Yang Xiao
  7. Shangda Chen
  8. Xiaoping Ouyang
  9. Huanyu Cheng
  10. Xiufeng Wang
License In Copyright (Rights Reserved)
Work Type Article
Publisher
  1. ACS applied materials & interfaces
Publication Date August 11, 2021
Publisher Identifier (DOI)
  1. https://doi.org/10.1021/acsami.1c08745
Deposited November 15, 2021

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Version 1
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  • Created
  • Added 97.Strain-tunable_microfluidic_crack_and_wrinkle_microvalves-ACS_AMI.pdf
  • Added Creator Ying Liu
  • Added Creator Min Cheng
  • Added Creator Jielong Huang
  • Added Creator Yangchengyi Liu
  • Added Creator Yao Chen
  • Added Creator Yang Xiao
  • Added Creator Shangda Chen
  • Added Creator Xiaoping Ouyang
  • Added Creator Huanyu Cheng
  • Added Creator Xiufeng Wang
  • Published
  • Updated
  • Updated
  • Updated