Beneficial effects of moderate heating on cardiovascular control in heart failure

This project examined the muscle sympathetic nerve activity (MSNA) response to heat stress and exercise in chronic heart failure (CHF). These data suggest that the MSNA response to heat stress is attenuated in CHF patients. The mild/moderate whole body heating induces a decrease in resting MSNA in CHF patients. Whole-body heat stress attenuated the blood pressure and sympathetic nerve responses to mechanoreceptor stimulation. The additional studies also show that radiofrequency catheter ablation (heating-induced coagulation necrosis) raised cardiac parasympathetic activity and decreased MSNA during the procedure. One day post-ablation, MSNA rose, cardiac parasympathetic activity fell. This project was supported by American Heart Association Grant 15GRNT24480051.

Files

Metadata

Work Title Beneficial effects of moderate heating on cardiovascular control in heart failure
Access
Open Access
Creators
  1. Jian Cui
Keyword
  1. heart failure, nervous system, sympathetic, heat
License All rights reserved
Work Type Dataset
DOI doi:10.18113/s16q10
Deposited December 27, 2018

Versions

Analytics

Collections

This resource is currently not in any collection.

Work History

Version 1
published

  • Created
  • Added AFibData_pg2.csv
  • Added CHFMSNAData_pg2.csv
  • Added AFibData.pdf
  • Added HeatEPRdata_pg2.csv
  • Added CHFMSNAData_pg3.csv
  • Added HeatEPRdata.pdf
  • Added CHFMSNAData.pdf
  • Added AFibData_pg1.csv
  • Added HeatEPRdata_pg1.csv
  • Added AFibData_pg3.csv
  • Added CHFMSNAData_pg1.csv
  • Added README.md
  • Added Creator Jian Cui
  • Published