Inverted meiosis and the evolution of sex by loss of complementation

Inverted meiosis, in which sister chromatids segregate before homologous chromosomes, is a common aberration of conventional meiosis (in which sister chromatids segregate after homologous chromosomes) and is routinely observed in certain species. This raises an evolutionary mystery: what is the adaptive advantage of the more common, conventional order of segregation in meiosis? I use a population genetic model to show that asexual mutants arising from inverted meiosis are relatively immune from the deleterious effects of loss of complementation (heterozygosity), unlike the asexual mutants arising from conventional meiosis, in which loss of complementation can outweigh the two-fold cost of meiosis. Hence, asexual reproduction can replace sexual reproduction with inverted meiosis, but not with conventional meiosis. The results are in line with analogous considerations on other alternative types of reproduction and support the idea that amphimixis is stable in spite of the two-fold cost of meiosis because loss of complementation in mutant asexuals outweigh the two-fold cost.

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Work Title Inverted meiosis and the evolution of sex by loss of complementation
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Open Access
Creators
  1. Marco Archetti
Keyword
  1. Amphimixis
  2. Apomixis
  3. Complementation
  4. Heterozygosity
  5. Inverted meiosis
  6. Lethal equivalent
  7. Meiosis
  8. Sex
  9. Sexual reproduction
License CC BY 4.0 (Attribution)
Work Type Article
Publisher
  1. Journal of Evolutionary Biology
Publication Date December 23, 2019
Publisher Identifier (DOI)
  1. https://doi.org/10.1111/jeb.13580
Deposited October 18, 2023

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Version 1
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  • Added Creator Marco Archetti
  • Added JEB_2020_inverted.pdf
  • Updated Publication Date, License Show Changes
    Publication Date
    • 6 December 2019
    License
    • https://creativecommons.org/licenses/by/4.0/
  • Updated Publication Date Show Changes
    Publication Date
    • 2022
  • Published
  • Updated Keyword, Publisher, Publisher Identifier (DOI), and 2 more Show Changes
    Keyword
    • Amphimixis, Apomixis, Complementation, Heterozygosity, Inverted meiosis, Lethal equivalent, Meiosis, Sex, Sexual reproduction
    Publisher
    • Journal of Evolutionary Biology
    Publisher Identifier (DOI)
    • https://doi.org/10.1111/jeb.13580
    Description
    • Inverted meiosis, in which sister chromatids segregate before homologous chromo- somes, is a common aberration of conventional meiosis (in which sister chromatids segregate after homologous chromosomes) and is routinely observed in certain spe- cies. This raises an evolutionary mystery: what is the adaptive advantage of the more common, conventional order of segregation in meiosis? I use a population genetic model to show that asexual mutants arising from inverted meiosis are relatively immune from the deleterious effects of loss of complementation (heterozygosity), unlike the asexual mutants arising from conventional meiosis, in which loss of com- plementation can outweigh the two-fold cost of meiosis. Hence, asexual reproduc- tion can replace sexual reproduction with inverted meiosis, but not with conventional meiosis. The results are in line with analogous considerations on other alternative types of reproduction and support the idea that amphimixis is stable in spite of the two-fold cost of meiosis because loss of complementation in mutant asexuals out- weigh the two-fold cost.
    • Inverted meiosis, in which sister chromatids segregate before homologous chromosomes, is a common aberration of conventional meiosis (in which sister chromatids segregate after homologous chromosomes) and is routinely observed in certain species. This raises an evolutionary mystery: what is the adaptive advantage of the more common, conventional order of segregation in meiosis? I use a population genetic model to show that asexual mutants arising from inverted meiosis are relatively immune from the deleterious effects of loss of complementation (heterozygosity), unlike the asexual mutants arising from conventional meiosis, in which loss of complementation can outweigh the two-fold cost of meiosis. Hence, asexual reproduction can replace sexual reproduction with inverted meiosis, but not with conventional meiosis. The results are in line with analogous considerations on other alternative types of reproduction and support the idea that amphimixis is stable in spite of the two-fold cost of meiosis because loss of complementation in mutant asexuals outweigh the two-fold cost.
    Publication Date
    • 2022
    • 2019-12-23
  • Updated