The Effects of L-Citrulline on a Cellular Level: Influencing Insulin Resistance

This pre-clinical study is aimed at examining the mechanism by which L-Citrulline may impact vascular activity and protein synthesis in a model of insulin-resistance. In L6 myotubes, L-Citrulline shows promising results of impacting protein synthesis through the mTOR pathway, as well as a potential effect on endothelial activity. Further research is needed to determine the exact function of L-Citrulline in a cellular model. This may eventually warrant translational research in Type 2 diabetic humans.

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Work Title The Effects of L-Citrulline on a Cellular Level: Influencing Insulin Resistance
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Open Access
Creators
  1. Joshua D Gray
  2. David L Williamson IV
License CC BY-NC-ND 4.0 (Attribution-NonCommercial-NoDerivatives)
Work Type Poster
Publication Date 2022
DOI doi:10.26207/x05m-az32
Deposited May 23, 2023

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Version 1
published

  • Created
  • Updated
  • Added Creator Joshua D Gray
  • Added Creator Emily Mross
  • Updated Acknowledgments Show Changes
    Acknowledgments
    • David Williamson
  • Added GRAY Honors Thesis Poster Presentation Final_Joshua Gray.pdf
  • Updated License Show Changes
    License
    • https://creativecommons.org/licenses/by-nc-nd/4.0/
  • Published
  • Updated

Version 2
published

  • Created
  • Deleted Creator Emily Mross
  • Published
  • Updated Acknowledgments Show Changes
    Acknowledgments
    • David Williamson
  • Added Creator David L Williamson IV
  • Updated