Skin Conduction Monitor and Pain Scores Values in Infants: Role of Genetic Polymorphisms Public

Skin conductance monitoring (SCM) was suggested previously as an indicator of the occurrence and severity of pain in the pediatric population. There has also been much interest in the A118G polymorphism of the morphine opioid receptor (MOR) and G1947A polymorphisms of the catechol-O-methyltransferase (COMT) with regards to its association with inter-individual differences in post-operative pain scores. The objective of our study was firstly, to determine the ability of SCM to predict the severity of acute post-operative pain in infants and secondly, to investigate the effect of MOR (A118G) and COMT (G1947A) polymorphisms on post operative pain scores and SCM values in the infant population.

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