Beneficial effects of moderate heating on cardiovascular control in heart failure Public

This project examined the muscle sympathetic nerve activity (MSNA) response to heat stress and exercise in chronic heart failure (CHF). These data suggest that the MSNA response to heat stress is attenuated in CHF patients. The mild/moderate whole body heating induces a decrease in resting MSNA in CHF patients. Whole-body heat stress attenuated the blood pressure and sympathetic nerve responses to mechanoreceptor stimulation. The additional studies also show that radiofrequency catheter ablation (heating-induced coagulation necrosis) raised cardiac parasympathetic activity and decreased MSNA during the procedure. One day post-ablation, MSNA rose, cardiac parasympathetic activity fell. This project was supported by American Heart Association Grant 15GRNT24480051.

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Title

Beneficial effects of moderate heating on cardiovascular control in heart failure

Creators

Project Description

This project examined the muscle sympathetic nerve activity (MSNA) response to heat stress and exercise in chronic heart failure (CHF). These data suggest that the MSNA response to heat stress is attenuated in CHF patients. The mild/moderate whole body heating induces a decrease in resting MSNA in CHF patients. Whole-body heat stress attenuated the blood pressure and sympathetic nerve responses to mechanoreceptor stimulation. The additional studies also show that radiofrequency catheter ablation (heating-induced coagulation necrosis) raised cardiac parasympathetic activity and decreased MSNA during the procedure. One day post-ablation, MSNA rose, cardiac parasympathetic activity fell. This project was supported by American Heart Association Grant 15GRNT24480051.

Data Description

This dataset includes three parts:

  • MSNA response to heat exposure in heart failure patients (CHFMSNAData files). This study examined muscle sympathetic nerve activity (MSNA) during mild heating and heat stress in chronic heart failure (CHF).
  • Exercise pressor reflex during whole body heating (HeatEPRdata files). This study examined MSNA, blood pressure responses to exercise under heat stress condition.
  • Sympathetic Responses by Radiofrequency Catheter Ablation of Atrial Fibrillation (AFibData files). This study examined the effects of radiofrequency catheter ablation (RFCA, heating-induced coagulation necrosis) performed in the left atrium on MSNA.

File Manifest / Data Structure

  • AFibData.pdf: Sympathetic Responses by Radiofrequency Catheter Ablation of Atrial Fibrillation
  • AFibData_pg1.csv: Data from table on pg. 1 of AFibData.pdf
  • AFibData_pg2.csv
  • AFibData_pg3.csv
  • CHFMSNAData.pdf: MSNA response to heat exposure in heart failure patients
  • CHFMSNAData_pg1.csv
  • CHFMSNAData_pg2.csv
  • CHFMSNAData_pg3.csv
  • HeatEPRdata.pdf: Exercise pressor reflex during whole body heating
  • HeatEPRdata_pg1.csv
  • HeatEPRdata_pg2.csv

Citation

If this data is used in a publication, please cite the following:

Cui, Jian (2019) "Beneficial effects of moderate heating on cardiovascular control in heart failure"

Licensing

All rights reserved

Metadata

Creator
Jian Cui
Keyword
heart failure, nervous system, sympathetic, heat
Rights
All rights reserved
Resource type
Dataset
Size
365 KB
Total items
12

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User Seth R Erickson has updated Beneficial effects of moderate heating on cardiovascular control in heart failure 4 months ago
User Seth R Erickson has updated Beneficial effects of moderate heating on cardiovascular control in heart failure 4 months ago
User Seth R Erickson has updated Beneficial effects of moderate heating on cardiovascular control in heart failure 4 months ago
User Jian Cui has attached README.md to Beneficial effects of moderate heating on cardiovascular control in heart failure 4 months ago
User Jian Cui has attached AFibData.pdf to Beneficial effects of moderate heating on cardiovascular control in heart failure 4 months ago
User Jian Cui has attached AFibData_pg3.csv to Beneficial effects of moderate heating on cardiovascular control in heart failure 4 months ago
User Jian Cui has attached AFibData_pg2.csv to Beneficial effects of moderate heating on cardiovascular control in heart failure 4 months ago
User Jian Cui has attached AFibData_pg1.csv to Beneficial effects of moderate heating on cardiovascular control in heart failure 4 months ago
User Jian Cui has attached HeatEPRdata.pdf to Beneficial effects of moderate heating on cardiovascular control in heart failure 4 months ago
User Jian Cui has attached CHFMSNAData_pg2.csv to Beneficial effects of moderate heating on cardiovascular control in heart failure 4 months ago
User Jian Cui has attached HeatEPRdata_pg1.csv to Beneficial effects of moderate heating on cardiovascular control in heart failure 4 months ago
User Jian Cui has attached CHFMSNAData_pg1.csv to Beneficial effects of moderate heating on cardiovascular control in heart failure 4 months ago
User Jian Cui has attached CHFMSNAData_pg3.csv to Beneficial effects of moderate heating on cardiovascular control in heart failure 4 months ago
User Jian Cui has attached /concern/file_sets/bvq27zn195 to Beneficial effects of moderate heating on cardiovascular control in heart failure 4 months ago
User Seth R Erickson has updated Beneficial effects of moderate heating on cardiovascular control in heart failure 4 months ago
User Seth R Erickson has updated Beneficial effects of moderate heating on cardiovascular control in heart failure 4 months ago
User Jian Cui has updated Beneficial effects of moderate heating on cardiovascular control in heart failure 5 months ago
User Jian Cui has attached representativeRecording.pdf to Beneficial effects of moderate heating on cardiovascular control in heart failure 5 months ago
User Jian Cui has updated Beneficial effects of moderate heating on cardiovascular control in heart failure 5 months ago
User Jian Cui has attached CHFMSNAData.pdf to Beneficial effects of moderate heating on cardiovascular control in heart failure 5 months ago
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User Jian Cui has deposited Beneficial effects of moderate heating on cardiovascular control in heart failure 5 months ago